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Translation of viral mRNAs that do not require eIF4E is blocked by the inhibitor 4EGI-1

High throughput screening has rendered new inhibitors of eukaryotic protein synthesis. One such molecule, 4EGI-1 has been reported to selectively block the initiation factor eIF4E. We have investigated the action of this inhibitor on translation directed by several viral mRNAs which, in principle, d...

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Bibliografski detalji
Izdano u:Virology
Glavni autori: Redondo, Natalia, García-Moreno, Manuel, Sanz, Miguel Angel, Carrasco, Luis
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Inc. 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7111898/
https://ncbi.nlm.nih.gov/pubmed/23870416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.06.008
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