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Translation without eIF2 Promoted by Poliovirus 2A Protease

Poliovirus RNA utilizes eIF2 for the initiation of translation in cell free systems. Remarkably, we now describe that poliovirus translation takes place at late times of infection when eIF2 is inactivated by phosphorylation. By contrast, translation directed by poliovirus RNA is blocked when eIF2 is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Redondo, Natalia, Sanz, Miguel Angel, Welnowska, Ewelina, Carrasco, Luis
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189197/
https://ncbi.nlm.nih.gov/pubmed/22003403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025699
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