AMP-activated protein kinase inhibits vascular smooth muscle cell proliferation and migration and vascular remodeling following injury

Vascular smooth muscle cell (VSMC) activation promotes a synthetic phenotype that underlies many vessel growth disorders. In this regard it has been suggested that the metabolic sensor adenosine 5′-monophosphate-activated protein kinase (AMPK) has significant antigrowth and antimetastatic properties...

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Hlavní autoři: Stone, Joshua D., Narine, Avinash, Shaver, Patti R., Fox, Jonathan C., Vuncannon, Jackson R., Tulis, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2013
Témata:
Vascular Biology and Microcirculation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774500/
https://ncbi.nlm.nih.gov/pubmed/23203966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00446.2012
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