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AMP-activated protein kinase inhibits vascular smooth muscle cell proliferation and migration and vascular remodeling following injury
Vascular smooth muscle cell (VSMC) activation promotes a synthetic phenotype that underlies many vessel growth disorders. In this regard it has been suggested that the metabolic sensor adenosine 5′-monophosphate-activated protein kinase (AMPK) has significant antigrowth and antimetastatic properties...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Physiological Society
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774500/ https://ncbi.nlm.nih.gov/pubmed/23203966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00446.2012 |
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