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Vinpocetine Suppresses Pathological Vascular Remodeling by Inhibiting Vascular Smooth Muscle Cell Proliferation and Migration

Abnormal vascular smooth muscle cell (SMC) activation is associated with various vascular disorders such as atherosclerosis, in-stent restenosis, vein graft disease, and transplantation-associated vasculopathy. Vinpocetine, a derivative of the alkaloid vincamine, has long been used as a cerebral blo...

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Detalhes bibliográficos
Main Authors: Cai, Yujun, Knight, Walter E., Guo, Shujie, Li, Jian-Dong, Knight, Peter A., Yan, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477207/
https://ncbi.nlm.nih.gov/pubmed/22915768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195446
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