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Vinpocetine Suppresses Pathological Vascular Remodeling by Inhibiting Vascular Smooth Muscle Cell Proliferation and Migration

Abnormal vascular smooth muscle cell (SMC) activation is associated with various vascular disorders such as atherosclerosis, in-stent restenosis, vein graft disease, and transplantation-associated vasculopathy. Vinpocetine, a derivative of the alkaloid vincamine, has long been used as a cerebral blo...

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Main Authors: Cai, Yujun, Knight, Walter E., Guo, Shujie, Li, Jian-Dong, Knight, Peter A., Yan, Chen
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477207/
https://ncbi.nlm.nih.gov/pubmed/22915768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.112.195446
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