Bilirubin Inhibits Neointima Formation and Vascular Smooth Muscle Cell Proliferation and Migration

Bilirubin is a heme metabolite generated by the concerted action of the enzymes heme oxygenase and biliverdin reductase. Although long considered a toxic byproduct of heme catabolism, recent preclinical, and clinical studies indicate the bilirubin exerts beneficial effects in the circulation. In the...

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Autores principales: Peyton, Kelly J., Shebib, Ahmad R., Azam, Mohammad A., Liu, Xiao-ming, Tulis, David A., Durante, William
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309974/
https://ncbi.nlm.nih.gov/pubmed/22470341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00048
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