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2′,3′-cAMP, 3′-AMP, and 2′-AMP inhibit human aortic and coronary vascular smooth muscle cell proliferation via A(2B) receptors

Rat vascular smooth muscle cells (VSMCs) from renal microvessels metabolize 2′,3′-cAMP to 2′-AMP and 3′-AMP, and these AMPs are converted to adenosine that inhibits microvascular VSMC proliferation via A(2B) receptors. The goal of this study was to test whether this mechanism also exists in VSMCs fr...

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Autors principals: Jackson, Edwin K., Ren, Jin, Gillespie, Delbert G.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154660/
https://ncbi.nlm.nih.gov/pubmed/21622827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00336.2011
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