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Regulation of 3’,5’-cAMP in Preglomerular Smooth Muscle and Endothelial Cells From Genetically-Hypertensive Rats

Our previous studies show that inhibition of phosphodiesterase 4 (PDE4) augments agonist-induced renovascular 3’,5’-cAMP secretion more in isolated, perfused kidneys from spontaneously hypertensive rats (SHR) versus Wistar-Kyoto normotensive rats (WKY); however, whether this is due to PDE4 inhibitio...

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Bibliographic Details
Main Authors: Cheng, Dongmei, Ren, Jin, Gillespie, Delbert G., Mi, Zaichuan, Jackson, Edwin K.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3011225/
https://ncbi.nlm.nih.gov/pubmed/20975032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.160176
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