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EXTRACELLULAR 2',3'-cAMP IS A POTENT INHIBITOR OF PREGLOMERULAR VASCULAR SMOOTH MUSCLE CELL AND MESANGIAL CELL GROWTH

Recently we discovered that intact kidneys release into the extracellular compartment 2',3'-cAMP (a positional isomer of 3',5'-cAMP with unknown pharmacology) and metabolize 2',3'-cAMP to 2'-AMP, 3'-AMP and adenosine. Because adenosine inhibits growth of vascu...

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Bibliografiske detaljer
Main Authors: Jackson, Edwin K., Ren, Jin, Gillespie, Delbert G., Dubey, Raghvendra K.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2892387/
https://ncbi.nlm.nih.gov/pubmed/20516392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.110.152454
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