Extracellular 3′,5′-cAMP-Adenosine Pathway Inhibits Glomerular Mesangial Cell Growth

Abnormal growth of glomerular mesangial cells (GMCs) contributes to the pathophysiology of many types of nephropathy. Because adenosine is an autocrine/paracrine factor that potentially could regulate GMC proliferation and because the extracellular 3′,5′-cAMP-adenosine pathway (i.e., the conversion...

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Bibliografiska uppgifter
Huvudupphovsmän: Dubey, Raghvendra K., Rosselli, Marinella, Gillespie, Delbert G., Mi, Zaichuan, Jackson, Edwin K.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Pharmacology and Experimental Therapeutics 2010
Ämnen:
Gastrointestinal, Hepatic, Pulmonary, and Renal
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879927/
https://ncbi.nlm.nih.gov/pubmed/20194527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.166371
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