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2′-AMP and 3′-AMP Inhibit Proliferation of Preglomerular Vascular Smooth Muscle Cells and Glomerular Mesangial Cells via A(2B) Receptors
Studies show that kidneys produce 2′,3′-cAMP, 2′,3′-cAMP is exported and metabolized to 2′-AMP and 3′-AMP, 2′-AMP and 3′-AMP are metabolized to adenosine, 2′,3′-cAMP inhibits proliferation of preglomerular vascular smooth muscle cells (PGVSMCs) and glomerular mesangial cells (GMCs), and A(2B) (not A...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3083111/ https://ncbi.nlm.nih.gov/pubmed/21270135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.178137 |
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