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2′-AMP and 3′-AMP Inhibit Proliferation of Preglomerular Vascular Smooth Muscle Cells and Glomerular Mesangial Cells via A(2B) Receptors

Studies show that kidneys produce 2′,3′-cAMP, 2′,3′-cAMP is exported and metabolized to 2′-AMP and 3′-AMP, 2′-AMP and 3′-AMP are metabolized to adenosine, 2′,3′-cAMP inhibits proliferation of preglomerular vascular smooth muscle cells (PGVSMCs) and glomerular mesangial cells (GMCs), and A(2B) (not A...

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Hlavní autoři: Jackson, Edwin K., Gillespie, Delbert G., Dubey, Raghvendra K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3083111/
https://ncbi.nlm.nih.gov/pubmed/21270135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.178137
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