TGF-β downregulates PTEN via activation of NF-κB in pancreatic cancer cells

TGF-β utilizes receptor-activated SMAD signaling to mediate growth suppression; however, non-SMAD signaling that modulates the TGF-β response in epithelial cells become apparent when the SMAD signaling is abrogated, a common occurrence in pancreatic cancers. Here, we examined whether TGF-β utilized...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Chow, Jimmy Y. C., Ban, Makiko, Wu, Helen L., Nguyen, Flang, Huang, Mei, Chung, Heekyung, Dong, Hui, Carethers, John M.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2010
Sujets:
Hormones and Signaling
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774494/
https://ncbi.nlm.nih.gov/pubmed/19940030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00344.2009
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires