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TGF-β downregulates PTEN via activation of NF-κB in pancreatic cancer cells
TGF-β utilizes receptor-activated SMAD signaling to mediate growth suppression; however, non-SMAD signaling that modulates the TGF-β response in epithelial cells become apparent when the SMAD signaling is abrogated, a common occurrence in pancreatic cancers. Here, we examined whether TGF-β utilized...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Physiological Society
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3774494/ https://ncbi.nlm.nih.gov/pubmed/19940030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00344.2009 |
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