Protein kinase D1 mediates NF-κB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells

The transcription factor NF-κB plays a critical role in inflammatory and cell death responses during acute pancreatitis. Previous studies in our laboratory demonstrated that protein kinase C (PKC) isoforms PKCδ and ɛ are key regulators of NF-κB activation induced by cholecystokinin-8 (CCK-8), tumor...

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Detalhes bibliográficos
Main Authors: Yuan, Jingzhen, Lugea, Aurelia, Zheng, Ling, Gukovsky, Ilya, Edderkaoui, Mouad, Rozengurt, Enrique, Pandol, Stephen J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Hormones and Signaling
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604803/
https://ncbi.nlm.nih.gov/pubmed/18845574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90452.2008
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