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RAS/ERK modulates TGFβ-regulated PTEN expression in human pancreatic adenocarcinoma cells
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is rarely mutated in pancreatic cancers, but its regulation by transforming growth factor (TGF)-β might mediate growth suppression and other oncogenic actions. Here, we examined the role of TGFβ and the effects of oncogenic K-RAS/ERK upo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4151289/ https://ncbi.nlm.nih.gov/pubmed/17638924 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgm159 |
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