RAS/ERK modulates TGFβ-regulated PTEN expression in human pancreatic adenocarcinoma cells

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is rarely mutated in pancreatic cancers, but its regulation by transforming growth factor (TGF)-β might mediate growth suppression and other oncogenic actions. Here, we examined the role of TGFβ and the effects of oncogenic K-RAS/ERK upo...

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Detaylı Bibliyografya
Asıl Yazarlar: Chow, Jimmy Y.C., Quach, Khai T., Cabrera, Betty L., Cabral, Jennifer A., Beck, Stayce E., Carethers, John M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2007
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4151289/
https://ncbi.nlm.nih.gov/pubmed/17638924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgm159
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