Role of calcium-independent phospholipase A(2)β in human pancreatic islet β-cell apoptosis

Death of β-cells due to apoptosis is an important contributor to β-cell dysfunction in both type 1 and type 2 diabetes mellitus. Previously, we described participation of the Group VIA Ca(2+)-independent phospholipase A(2) (iPLA(2)β) in apoptosis of insulinoma cells due to ER stress. To examine whet...

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Hlavní autoři: Lei, Xiaoyong, Zhang, Sheng, Bohrer, Alan, Barbour, Suzanne E., Ramanadham, Sasanka
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3774083/
https://ncbi.nlm.nih.gov/pubmed/23074238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00234.2012
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