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Investigation of Rett Syndrome using pluripotent stem cells

Rett Syndrome (RTT) is one of most prevalent female neurodevelopmental disorders. De novo mutations in X-linked MECP2 are mostly responsible for RTT. Since the identification of MeCP2 as the underlying cause of RTT, murine models have contributed to understanding the pathophysiology of RTT and funct...

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Hlavní autoři: Dajani, Rana, Koo, Sung-Eun, Sullivan, Gareth J., Park, In-Hyun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773984/
https://ncbi.nlm.nih.gov/pubmed/23744605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24597
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