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Investigation of Rett Syndrome using pluripotent stem cells

Rett Syndrome (RTT) is one of most prevalent female neurodevelopmental disorders. De novo mutations in X-linked MECP2 are mostly responsible for RTT. Since the identification of MeCP2 as the underlying cause of RTT, murine models have contributed to understanding the pathophysiology of RTT and funct...

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Bibliografiske detaljer
Main Authors: Dajani, Rana, Koo, Sung-Eun, Sullivan, Gareth J., Park, In-Hyun
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3773984/
https://ncbi.nlm.nih.gov/pubmed/23744605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24597
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