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Humanized Murine Model for HBV and HCV Using Human Induced Pluripotent Stem Cells

Infection of hepatitis B virus (HBV) and hepatitis C virus (HCV) results in heterogeneous outcomes from acute asymptomatic infection to chronic infection leading to cirrhosis and hepatocellular carcinoma (HCC). In vitro models using animal hepatocytes, human HCC cell lines, or in vivo transgenic mou...

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Detalhes bibliográficos
Main Authors: Zhou, Xiao-Ling, Sullivan, Gareth J., Sun, Pingnan, Park, In-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3731984/
https://ncbi.nlm.nih.gov/pubmed/22370780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12272-012-0206-8
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