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Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome
Rett syndrome (RTT) is one of the most prevalent female neurodevelopmental disorders that cause severe mental retardation. Mutations in methyl CpG binding protein 2 (MeCP2) are mainly responsible for RTT. Patients with classical RTT exhibit normal development until age 6–18 mo, at which point they b...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161557/ https://ncbi.nlm.nih.gov/pubmed/21807996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018979108 |
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