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Neuronal maturation defect in induced pluripotent stem cells from patients with Rett syndrome

Rett syndrome (RTT) is one of the most prevalent female neurodevelopmental disorders that cause severe mental retardation. Mutations in methyl CpG binding protein 2 (MeCP2) are mainly responsible for RTT. Patients with classical RTT exhibit normal development until age 6–18 mo, at which point they b...

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Autori principali: Kim, Kun-Yong, Hysolli, Eriona, Park, In-Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161557/
https://ncbi.nlm.nih.gov/pubmed/21807996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018979108
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