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X-Chromosome Inactivation in Rett Syndrome Human Induced Pluripotent Stem Cells
Rett syndrome (RTT) is a neurodevelopmental disorder that affects girls due primarily to heterozygous mutations in the X-linked gene encoding methyl-CpG binding protein 2 (MECP2). Random X-chromosome inactivation (XCI) results in cellular mosaicism in which some cells express wild-type (WT) MECP2 wh...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Research Foundation
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311266/ https://ncbi.nlm.nih.gov/pubmed/22470355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fpsyt.2012.00024 |
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