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Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC

It has been shown that human and murine fibroblasts can be reprogrammed by ectopic expression of transcription factors using viral vectors. For the purpose of human therapeutic applications, the integration of viral transgenes into the genome is unlikely to be accepted. We therefore produced recombi...

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Bibliografski detalji
Glavni autori: Pan, Chuanying, Lu, Baisong, Chen, Hong, Bishop, Colin E.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772671/
https://ncbi.nlm.nih.gov/pubmed/19669668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-009-9680-6
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