Spermatogonial stem cells and progenitors are refractory to reprogramming to pluripotency by the transcription factors Oct3/4, c-Myc, Sox2 and Klf4

The male germinal lineage, which is defined as unipotent, produces sperm through spermatogenesis. However, embryonic primordial germ cells and postnatal spermatogonial stem cells (SSCs) can change their fate and convert to pluripotency in culture when they are not controlled by the testicular microe...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Corbineau, Sébastien, Lassalle, Bruno, Givelet, Maelle, Souissi-Sarahoui, Inès, Firlej, Virginie, Romeo, Paul Henri, Allemand, Isabelle, Riou, Lydia, Fouchet, Pierre
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354640/
https://ncbi.nlm.nih.gov/pubmed/28052023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.14327
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