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Gene expression of OCT4, SOX2, KLF4 and MYC (OSKM) induced pluripotent stem cells: identification for potential mechanisms

BACKGROUND: Somatic cells could be reprogrammed to induced pluripotent stem cells (iPS) by ectopic expression of OCT4, SOX2, KLF4 and MYC (OSKM). We aimed to gain insights into the early mechanisms underlying the induction of pluripotency. METHODS: GSE28688 containing 14 gene expression profiles wer...

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Detalhes bibliográficos
Publicado no:Diagn Pathol
Main Authors: Cai, Yanning, Dai, Xianhua, Zhang, Qianhua, Dai, Zhiming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4414430/
https://ncbi.nlm.nih.gov/pubmed/25907774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13000-015-0263-7
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