Novel AKT phosphorylation sites identified in the pluripotency factors OCT4, SOX2 and KLF4

The four OSKM factors OCT4, SOX2, KLF4 and c-MYC are key transcription factors modulating pluripotency, self-renewal and tumorigenesis in stem cells. However, although their transcriptional targets have been extensively studied, little is known about how these factors are regulated at the posttransl...

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Bibliographic Details
Published in:Cell Cycle
Main Authors: Malak, Peter N, Dannenmann, Benjamin, Hirth, Alexander, Rothfuss, Oliver C, Schulze-Osthoff, Klaus
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4825772/
https://ncbi.nlm.nih.gov/pubmed/26654770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1104444
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