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Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC

It has been shown that human and murine fibroblasts can be reprogrammed by ectopic expression of transcription factors using viral vectors. For the purpose of human therapeutic applications, the integration of viral transgenes into the genome is unlikely to be accepted. We therefore produced recombi...

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書目詳細資料
Main Authors: Pan, Chuanying, Lu, Baisong, Chen, Hong, Bishop, Colin E.
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772671/
https://ncbi.nlm.nih.gov/pubmed/19669668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-009-9680-6
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