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Reprogramming human fibroblasts using HIV-1 TAT recombinant proteins OCT4, SOX2, KLF4 and c-MYC

It has been shown that human and murine fibroblasts can be reprogrammed by ectopic expression of transcription factors using viral vectors. For the purpose of human therapeutic applications, the integration of viral transgenes into the genome is unlikely to be accepted. We therefore produced recombi...

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Autors principals: Pan, Chuanying, Lu, Baisong, Chen, Hong, Bishop, Colin E.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772671/
https://ncbi.nlm.nih.gov/pubmed/19669668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-009-9680-6
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