Destabilization of the Epidermal Growth Factor Receptor (EGFR) by a Peptide That Inhibits EGFR Binding to Heat Shock Protein 90 and Receptor Dimerization

An eight-amino acid segment is known to be responsible for the marked difference in the rates of degradation of the EGF receptor (ErbB1) and ErbB2 upon treatment of cells with the Hsp90 inhibitor geldanamycin. We have scrambled the first six amino acids of this segment of the EGF receptor (EGFR), wh...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Ahsan, Aarif, Ray, Dipankar, Ramanand, Susmita G., Hegde, Ashok, Whitehead, Christopher, Rehemtulla, Alnawaz, Morishima, Yoshihiro, Pratt, William B., Osawa, Yoichi, Lawrence, Theodore S., Nyati, Mukesh K.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
Matèries:
Protein Synthesis and Degradation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3772236/
https://ncbi.nlm.nih.gov/pubmed/23897823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.492280
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars