Regulation of EGFR Protein Stability by the HECT-type Ubiquitin Ligase SMURF2

Epidermal growth factor receptor (EGFR) is overexpressed in a variety of epithelial tumors and is considered to be an important therapeutic target. Although gene amplification is responsible for EGFR overexpression in certain human malignancies including lung and head and neck cancers, additional mo...

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Autors principals: Ray, Dipankar, Ahsan, Aarif, Helman, Abigail, Chen, Guoan, Hegde, Ashok, Gurjar, Susmita Ramanand, Zhao, Lili, Kiyokawa, Hiroaki, Beer, David G, Lawrence, Theodore S, Nyati, Mukesh K
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press Inc. 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132843/
https://ncbi.nlm.nih.gov/pubmed/21750651
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