Regulation of EGFR Protein Stability by the HECT-type Ubiquitin Ligase SMURF2

Epidermal growth factor receptor (EGFR) is overexpressed in a variety of epithelial tumors and is considered to be an important therapeutic target. Although gene amplification is responsible for EGFR overexpression in certain human malignancies including lung and head and neck cancers, additional mo...

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Detalhes bibliográficos
Main Authors: Ray, Dipankar, Ahsan, Aarif, Helman, Abigail, Chen, Guoan, Hegde, Ashok, Gurjar, Susmita Ramanand, Zhao, Lili, Kiyokawa, Hiroaki, Beer, David G, Lawrence, Theodore S, Nyati, Mukesh K
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3132843/
https://ncbi.nlm.nih.gov/pubmed/21750651
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