טוען...
The HECT E3 ligase Smurf2 is required for Mad2-dependent spindle assembly checkpoint
Activation of the anaphase-promoting complex/cyclosome (APC/C) by Cdc20 is critical for the metaphase–anaphase transition. APC/C-Cdc20 is required for polyubiquitination and degradation of securin and cyclin B at anaphase onset. The spindle assembly checkpoint delays APC/C-Cdc20 activation until all...
שמור ב:
| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
The Rockefeller University Press
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568023/ https://ncbi.nlm.nih.gov/pubmed/18852296 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200801049 |
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