Mechanism-Based Epigenetic Chemosensitization Therapy of Diffuse Large B Cell Lymphoma

Although aberrant DNA methylation patterning is a hallmark of cancer, the relevance of targeting DNA methyltransferases (DNMT) remains unclear for most tumors. In diffuse large B-cell lymphoma (DLBCL) we observed that chemo-resistance is associated with aberrant DNA methylation programming. Prolonge...

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Main Authors: Clozel, Thomas, Yang, ShaoNing, Elstrom, Rebecca L., Tam, Wayne, Martin, Peter, Kormaksson, Matthias, Banerjee, Samprit, Vasanthakumar, Aparna, Culjkovic, Biljana, Scott, David W., Wyman, Sarah, Leser, Michael, Shaknovich, Rita, Chadburn, Amy, Tabbo, Fabrizio, Godley, Lucy A., Gascoyne, Randy D., Borden, Katherine L., Inghirami, Giorgio, Leonard, John P., Melnick, Ari, Cerchietti, Leandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770813/
https://ncbi.nlm.nih.gov/pubmed/23955273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0117
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