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DNA Topoisomerases Participate in Fragility of the Oncogene RET

Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under conditions that partially inhibit DNA replication...

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Bibliografische gegevens
Hoofdauteurs: Dillon, Laura W., Pierce, Levi C. T., Lehman, Christine E., Nikiforov, Yuri E., Wang, Yuh-Hwa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770543/
https://ncbi.nlm.nih.gov/pubmed/24040417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075741
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