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DNA Topoisomerases Participate in Fragility of the Oncogene RET
Fragile site breakage was previously shown to result in rearrangement of the RET oncogene, resembling the rearrangements found in thyroid cancer. Common fragile sites are specific regions of the genome with a high susceptibility to DNA breakage under conditions that partially inhibit DNA replication...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3770543/ https://ncbi.nlm.nih.gov/pubmed/24040417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075741 |
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