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Role of DNA secondary structures in fragile site breakage along human chromosome 10

The formation of alternative DNA secondary structures can result in DNA breakage leading to cancer and other diseases. Chromosomal fragile sites, which are regions of the genome that exhibit chromosomal breakage under conditions of mild replication stress, are predicted to form stable DNA secondary...

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Detalhes bibliográficos
Main Authors: Dillon, Laura W., Pierce, Levi C. T., Ng, Maggie C. Y., Wang, Yuh-Hwa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596854/
https://ncbi.nlm.nih.gov/pubmed/23297364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds561
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