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DNA Instability at Chromosomal Fragile Sites in Cancer
Human chromosomal fragile sites are specific genomic regions which exhibit gaps or breaks on metaphase chromosomes following conditions of partial replication stress. Fragile sites often coincide with genes that are frequently rearranged or deleted in human cancers, with over half of cancer-specific...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers Ltd.
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944998/ https://ncbi.nlm.nih.gov/pubmed/21286310 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/138920210791616699 |
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