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DNA Breaks at Fragile Sites Generate Oncogenic RET/PTC Rearrangements in Human Thyroid Cells

Human chromosomal fragile sites are regions of the genome that are prone to DNA breakage, and are classified as common or rare, depending on their frequency in the population. Common fragile sites frequently coincide with the location of genes involved in carcinogenic chromosomal translocations, sug...

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Detaylı Bibliyografya
Asıl Yazarlar: Gandhi, Manoj, Dillon, Laura W., Pramanik, Sreemanta, Nikiforov, Yuri E., Wang, Yuh-Hwa
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2855398/
https://ncbi.nlm.nih.gov/pubmed/20101222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.502
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