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Secondary structure formation and DNA instability at fragile site FRA16B

Human chromosomal fragile sites are specific loci that are especially susceptible to DNA breakage following conditions of partial replication stress. They often are found in genes involved in tumorigenesis and map to over half of all known cancer-specific recurrent translocation breakpoints. While t...

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Autori principali: Burrow, Allison A., Marullo, Allison, Holder, Lindsay R., Wang, Yuh-Hwa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875025/
https://ncbi.nlm.nih.gov/pubmed/20071743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1245
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