A Genome-wide Map of CTCF Multivalency Redefines the CTCF Code

The “CTCF code” hypothesis posits that CTCF pleiotropic functions are driven by recognition of diverse sequences through combinatorial use of its 11 zinc fingers (ZFs). This model, however, is supported by in vitro binding studies of a limited number of sequences. To study CTCF multivalency in vivo,...

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Main Authors: Nakahashi, Hirotaka, Kieffer Kwon, Kyong-Rim, Resch, Wolfgang, Vian, Laura, Dose, Marei, Stavreva, Diana, Hakim, Ofir, Pruett, Nathanael, Nelson, Steevenson, Yamane, Arito, Qian, Jason, Dubois, Wendy, Welsh, Scott, Phair, Robert D., Pugh, B. Franklin, Lobanenkov, Victor, Hager, Gordon L., Casellas, Rafael
Format: Artigo
Sprog:Inglês
Udgivet: 2013
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3770538/
https://ncbi.nlm.nih.gov/pubmed/23707059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.024
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