Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation

A key finding of the ENCODE project is that the enhancer landscape of mammalian cells undergoes marked alterations during ontogeny. However, the nature and extent of these changes are unclear. As part of the NIH Mouse Regulome Project, we here combined DNaseI hypersensitivity, ChIP-Seq, and ChIA-PET...

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Auteurs principaux: Kwon, Kyong-Rim Kieffer, Tang, Zhonghui, Mathe, Ewy, Qian, Jason, Sung, Myong-Hee, Li, Guoliang, Resch, Wolfgang, Baek, Songjoon, Pruett, Nathanael, Grøntved, Lars, Vian, Laura, Nelson, Steevenson, Zare, Hossein, Hakim, Ofir, Reyon, Deepak, Yamane, Arito, Nakahashi, Hirotaka, Kovalchuk, Alexander L., Zou, Jizhong, Joung, J. Keith, Sartorelli, Vittorio, Wei, Chia-Lin, Ruan, Xiaoan, Hager, Gordon L., Ruan, Yijun, Casellas, Rafael
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905448/
https://ncbi.nlm.nih.gov/pubmed/24360274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.039
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