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Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation

A key finding of the ENCODE project is that the enhancer landscape of mammalian cells undergoes marked alterations during ontogeny. However, the nature and extent of these changes are unclear. As part of the NIH Mouse Regulome Project, we here combined DNaseI hypersensitivity, ChIP-Seq, and ChIA-PET...

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Main Authors: Kwon, Kyong-Rim Kieffer, Tang, Zhonghui, Mathe, Ewy, Qian, Jason, Sung, Myong-Hee, Li, Guoliang, Resch, Wolfgang, Baek, Songjoon, Pruett, Nathanael, Grøntved, Lars, Vian, Laura, Nelson, Steevenson, Zare, Hossein, Hakim, Ofir, Reyon, Deepak, Yamane, Arito, Nakahashi, Hirotaka, Kovalchuk, Alexander L., Zou, Jizhong, Joung, J. Keith, Sartorelli, Vittorio, Wei, Chia-Lin, Ruan, Xiaoan, Hager, Gordon L., Ruan, Yijun, Casellas, Rafael
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905448/
https://ncbi.nlm.nih.gov/pubmed/24360274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2013.11.039
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