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MLL Becomes Functional through Intra-Molecular Interaction Not by Proteolytic Processing
The mixed lineage leukemia (MLL) protein is an epigenetic transcriptional regulator that controls proliferative expansion of immature hematopoietic progenitors, whose aberrant activation triggers leukemogenesis. A mature MLL protein is produced by formation of an intra-molecular complex and proteoly...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3769346/ https://ncbi.nlm.nih.gov/pubmed/24040009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073649 |
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