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Proteolytically cleaved MLL subunits are susceptible to distinct degradation pathways
The mixed lineage leukemia (MLL) proto-oncogenic protein is a histone-lysine N-methyltransferase that is produced by proteolytic cleavage and self-association of the respective functionally distinct subunits (MLL(N) and MLL(C)) to form a holocomplex involved in epigenetic transcriptional regulation....
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Company of Biologists
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113671/ https://ncbi.nlm.nih.gov/pubmed/21670200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.080523 |
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