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Menin critically links MLL proteins with LEDGF on cancer-associated target genes

Menin displays the unique ability to either promote oncogenic function in the hematopoietic lineage or suppress tumorigenesis in the endocrine lineage, however its molecular mechanism of action has not been defined. We demonstrate here that these discordant functions are unified by menin's abil...

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Main Authors: Yokoyama, Akihiko, Cleary, Michael L.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692591/
https://ncbi.nlm.nih.gov/pubmed/18598942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.05.003
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