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MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters
Mixed-lineage leukemia (MLL) maintains the expression of cellular memory genes during development, while leukemic MLL fusion proteins aberrantly maintain expression of hematopoietic stem cell program genes such as HOXA9 to cause leukemia. However, the molecular mechanism of gene activation is unclea...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985622/ https://ncbi.nlm.nih.gov/pubmed/24465000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt1394 |
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