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Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets

Polycomb Group (PcG) proteins are epigenetic repressors of gene expression. The Drosophila Additional sex combs (Asx) gene and its mammalian homologs exhibit PcG function in genetic assays; however, the mechanism by which Asx family proteins mediate gene repression is not well understood. ASXL2, one...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lai, Hsiao-Lei, Wang, Q. Tian
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767597/
https://ncbi.nlm.nih.gov/pubmed/24040135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073983
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