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The Role of Additional Sex Combs-Like Proteins in Cancer
Additional sex combs-like (ASXL) proteins are mammalian homologs of Addition of sex combs (Asx), a protein that regulates the balance of trithorax and Polycomb function in Drosophila. All three ASXL family members (ASXL1, ASXL2, and ASXL3) are affected by somatic or de novo germline mutations in can...
Wedi'i Gadw mewn:
Cyhoeddwyd yn: | Cold Spring Harb Perspect Med |
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Prif Awduron: | , |
Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Cold Spring Harbor Laboratory Press
2016
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Pynciau: | |
Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5046687/ https://ncbi.nlm.nih.gov/pubmed/27527698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026526 |
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