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The Role of Additional Sex Combs-Like Proteins in Cancer

Additional sex combs-like (ASXL) proteins are mammalian homologs of Addition of sex combs (Asx), a protein that regulates the balance of trithorax and Polycomb function in Drosophila. All three ASXL family members (ASXL1, ASXL2, and ASXL3) are affected by somatic or de novo germline mutations in can...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cold Spring Harb Perspect Med
Prif Awduron: Micol, Jean-Baptiste, Abdel-Wahab, Omar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046687/
https://ncbi.nlm.nih.gov/pubmed/27527698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026526
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