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The Role of Additional Sex Combs-Like Proteins in Cancer
Additional sex combs-like (ASXL) proteins are mammalian homologs of Addition of sex combs (Asx), a protein that regulates the balance of trithorax and Polycomb function in Drosophila. All three ASXL family members (ASXL1, ASXL2, and ASXL3) are affected by somatic or de novo germline mutations in can...
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| izdano v: | Cold Spring Harb Perspect Med |
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| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Cold Spring Harbor Laboratory Press
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5046687/ https://ncbi.nlm.nih.gov/pubmed/27527698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026526 |
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