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Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets
Polycomb Group (PcG) proteins are epigenetic repressors of gene expression. The Drosophila Additional sex combs (Asx) gene and its mammalian homologs exhibit PcG function in genetic assays; however, the mechanism by which Asx family proteins mediate gene repression is not well understood. ASXL2, one...
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3767597/ https://ncbi.nlm.nih.gov/pubmed/24040135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073983 |
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