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Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets

Polycomb Group (PcG) proteins are epigenetic repressors of gene expression. The Drosophila Additional sex combs (Asx) gene and its mammalian homologs exhibit PcG function in genetic assays; however, the mechanism by which Asx family proteins mediate gene repression is not well understood. ASXL2, one...

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Detalhes bibliográficos
Main Authors: Lai, Hsiao-Lei, Wang, Q. Tian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767597/
https://ncbi.nlm.nih.gov/pubmed/24040135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0073983
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