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Cotranslational folding of membrane proteins probed by arrest-peptide–mediated force measurements

Polytopic membrane proteins are inserted cotranslationally into target membranes by ribosome–translocon complexes. It is, however, unclear when during the insertion process specific interactions between the transmembrane helices start to form. Here, we use a recently developed in vivo technique to m...

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Hlavní autoři: Cymer, Florian, von Heijne, Gunnar
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767533/
https://ncbi.nlm.nih.gov/pubmed/23959879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306787110
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