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Exploration of the Arrest Peptide Sequence Space Reveals Arrest-enhanced Variants

Translational arrest peptides (APs) are short stretches of polypeptides that induce translational stalling when synthesized on a ribosome. Mechanical pulling forces acting on the nascent chain can weaken or even abolish stalling. APs can therefore be used as in vivo force sensors, making it possible...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Cymer, Florian, Hedman, Rickard, Ismail, Nurzian, von Heijne, Gunnar
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400336/
https://ncbi.nlm.nih.gov/pubmed/25713070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.641555
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